醋酸（ch3cooh）是一種弱酸，常見于家用醋中，而碳酸氫鈉（nahco3）又稱小蘇打，是一種堿性化合物。
將這兩種物質混合在一起時，醋酸會向碳酸氫鈉捐獻一個質子（h+）。這種質子轉移反應會形成碳酸（h2co3），碳酸不穩定，會迅速分解成二氧化碳（co2）和水（h2o）。該方程式可分解為幾個步驟：
步驟 1：ch3cooh + nahco3 → ch3coo-na+ + h2co3
步驟 2：h2co3 → co2 + h2o
總的來說： ch3cooh + nahco3 → co2 + h2o + nach3coo
因此，總的來說，醋酸和碳酸氫鈉混合后會產生二氧化碳氣體，從而導致該反應中常見的起泡或氣泡效果。其他產物是水和。

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